Pharmaceutical API, or active pharma ingredients, is the core aspect of the pharma industry. Whether we need medicine for diabetes, heart failure, or even cancer, we need suitable and high-quality APIs. Regardless of the high manufacturing cost and strict policies, the market for API manufacturing has reached a great height. And why not?
Whether manufacturing the ongoing basic medicine or finding the drugs for pandemic situations, API or active pharma ingredients are involved at every stage of medicine development. But what exactly is API, its types, and the commonly used APIs in the pharma industry? Let’s explore answers to all such questions in our blog below!
What is Pharmaceutical API?
Pharmaceutical API or active pharma ingredients are the raw materials used to manufacture medicine for the disease. APIs are the active ingredients that produce the required effects on the human body. Sometimes, a common API is used with other APIs to form the required drug.
The pharmaceutical API manufacturers combine several chemical compounds to create the required APIs. However, before becoming the API, those chemical compounds undergo a stage called intermediates. Those intermediates then form API after thorough testing and quality analysis.
Types of Active Pharmaceutical Ingredients
Now that we know APIs’ basics let us quickly discuss their types. So, pharmaceutical APIs can be classified into two major categories, viz., synthetic and natural.
Synthetic APIs are also known as small molecules API. Around 66% of the pharmaceutical APIs available in the market today are synthetic APIs. On the other hand, natural pharmaceutical APIs are used for creating biologics. The trend of biologics has increased exponentially in recent times. However, they are still less in number when compared to synthetic APIs.
Common Concerns of Outsourcing APIs
APIs are the essential components of medicine production. However, many companies fear outsourcing API manufacturing due to multiple reasons. The most common and biggest reason for them is the quality of API manufacturing.
Many active pharma ingredients manufacturing companies offer poor-quality APIs that, if used, can lead to inefficient medicines and fatalities. That’s why it is very important to outsource your API manufacturing to a reputed company having the required resources and knowledge.
That’s Where Bulat Pharmaceuticals Comes Into Play!
Bulat Pharmaceutical is a reliable technological enterprise having experience in the R&D, production, and marketing of pharmaceutical raw materials. Whether intermediate, raw materials, or APIs, we can deliver everything related to the pharma business under one roof.
Our experts create and test APIs through various quality checks and inspection methods, ensuring high-quality APIs. You can connect with us to share your requirements, and we will deliver products matching your expectations.
List of Commonly Used Pharmaceutical APIs
Here’s a list of all the active pharma ingredients we can manufacture at Bulat Pharmaceutical.
|Products||CAS||Application / Usage|
|Alogliptin Benzoate||850649-62-6||Diabetes drug|
|Trelagliptin succinate||1029877-94-8||Diabetes drug|
|LCZ696 (Valsartan+Sacubitril)||936623-90-4||Antihypertensive drug|
|Tenofovir Alafenamide Fumarate||379270-38-9||Antiviral drug|
|Daclatasvir dihydrochloride||1009119-65-6||Antiviral drug|
|Velpatasvir-Co-Povidone (1:1)||N/A||Antiviral drug|
|Ledipasvir: Copovidone Solid Dispersion||N/A||Antiviral drug|
|Apremilast||608141-41-9||Psoriatic arthritis drug|
|Cefquinome Sulfate||118443-89-3||Veterinary drug|
|Ceftiofur sodium||104010-37-9||Veterinary drug|
|Flunitine meglumine||Veterinary drug|
|Colistin sulfate||Veterinary drug|
|NMN（BETA-NICOTINAMIDE MONONUCLEOTIDE)||1094-61-7||Health Care|
|PQQ（ Methoxatin disodium salt)||122628-50-6||Health Care|
|Abiraterone Acetate (IP/USP)||154229-18-2||Prostate cancer patients|
|Ibrutinib (IHS)||936563-96-1||Lung cancer|
|Axitinib (IHS)||319460-85-0||renal cell carcinoma|
|Crizotinib (IHS)||877399-52-5||Lung cancer|
|Osimertinib (IHS)||1421373-66-1||Lung cancer drug|
|Lapatinib di tosylate||231277-92-2||Breast cancer|
|Gemcitabine HCL (USP / BP / Ph.Eur)||122111-03-9||Breast cancer|
|Pemetrexed Disodium (USP)||150399-23-8||Lung cancer|
|Brigatinib (IH)||1197953-54-0||Lung cancer|
|Nilutamide (Ph. Eur)||63612-50-0||Prostate cancer|
|Carmustine (USP / BP / Ph.Eur)||154-93-8||Chemotherapy|
|Cisplatin (USP / BP / IP / Ph.Eur.)||15663-27-1||Chemotherapy|
|Carboplatin ( USP / BP / Ph.Eur)||41575-94-4||Chemotherapy|
|Oxaliplatin ( USP / BP / Ph.Eur)||63121-00-6||Colorectal cancer|
|Docetaxel Tryhydrate( BP / IP / Ph.Eur.)||148408-66-6||Breast cancer|
|Melphalan (USP/IP)||148-82-3||Ovarian cancer|
|Temozolomide (USP/IP)||85622-93-1||Brain cancer|
|Pazopanib hydrochloride (IHS)||635702-64-6||Renal cell carcinoma|
|Sunitinib maleate (IHS)||341031-54-7||Antitumor|
|Pemetrexed disodium (IP)||150399-23-8||Antitumor|
|Pemetrexed disodium heptahydrate (USP/EP)||357166-29-1||Antitumor|
|Nilotinib Hydrochloride (HIS)||923288-95-3||CML|
|Anastrazole (USP/IP)||120511-73-1||Breast cancer|
|Imatinib Mesylate (IP)||220127-57-1||Antitumor|
|Letrazole(USP / BP / Ph.Eur)||112809-51-5||Antitumor|
|Erlotinib Hydrochoride (IHS)||183319-69-9||Lung cancer|
|Gemcitabine Hydrochloride (USP / BP / Ph.Eur)||122111-03-9||Antitumor|
|Baloxavir marboxil||1985606-14-1||Antiviral Drug|
|Tianeptine sodium salt||30123-17-2||Antidepressants Drug|
|Clascoterone||19608-29-8||Androgen Receptor Inhibitor|
|Nafamostat Mesilate||82956-11-4||Antiviral Drug|
|Creatine Phosphate Disodium Salt||922-32-7||Health Care|
|Nicotinamide Riboside Chloride||23111-00-4||Health Care|
|TPP- Thiazole||1352002-58-4||Health Care|
|Finerenone||1050477-31-0||Endocrine based drug|
|BISOXATIN ACETATE||14008-48-1||Constipation drug|
|AMG510||2252403-56-6||Non-Small Cell Lung Cancer|
|L – Carnosine||305-84-0||Healthy Product|
To conclude, Pharmaceutical APIs are the most common aspects in the pharma sector. Every medicine, whether heart disease, liver failure, or even psoriasis are made using high-quality APIs. These active pharma ingredients can be categorized as synthetic or natural depending on the molecular structure. If you are planning to outsource your API manufacturing process, then Bulat Pharmacueticals can be your partner. Reach us to explore much more about aPI and begin your manufacturing process right away!