Valsartan: Everything You Need to Know

Valsartan api structure

What is Valsartan

It is a medication that belongs to the class of drugs known as angiotensin ll receptor blockers. Valsartan is used for the treatment of high blood pressure and heart failure. This drug works by blocking the action of the hormone called angiotensin II which narrows the blood vessels and increases blood pressure. By blocking angiotensin, Valsartan can relax and widen the blood vessels and lower the blood pressure. 

This article will give you a quick idea about Valsartan and every fact that you must know before using this drug. 

Use of Valsartan

This medication is used for treating high blood pressure as well as heart failure. Valsartan belongs to the class of drugs called angiotensin receptor blockers, which lowers blood pressure and improves blood flow. By blocking angiotensin ll, it helps to relax and widen the blood vessels that reduce blood pressure. 

Apart from treating hypertension and heart failure, this drug is often used to prevent cardiovascular events like stroke and heart attack.

It is crucial to take Valsartan as directed by the healthcare provider, and do not stop taking your medication without the consultation of your healthcare provider. Like any other medication, Valsartan can cause side effects, including dizziness, fatigue, headache, and gastrointestinal problems. In case you experience any of these side effects, then immediately reach out to the healthcare provider. 

Side Effects of Valsartan

It is a medication commonly used to treat high blood pressure and heart failure. Like any other medication, Valsartan API can cause side effects, including

  • Dizziness is one of those common side effects of Valsartan, especially when you first start taking the medication. You may feel dizzy or lightheaded, and later on, that can affect your balance and coordination. 
  • You may feel weak after taking Valsartan, especially if you take any other medication s for high blood pressure or heart failure. It can also cause headaches, especially during the first few days of your treatment. 
  • This drug can also cause diarrhoea, even though it is less common than other side effects. 
  • Valsartan can cause muscle pain as well as back pain, especially during the first few weeks of the treatment. 
  • It can increase the potassium levels in the blood. Valsartan can be quite dangerous, especially for people with kidney problems. 
  • It can cause fetal toxicity, so it is advised not to take it during pregnancy. 

It is important to note that all these side effects are not exhaustive, and they may cause other side effects as well. If you experience any after taking Valsartan, it is very important to talk to the doctor as soon as possible. 

Precautions for Valsartan 

There are some safety measures to be followed by API manufacturers when using valsartan, just like with any medication:

Allergies: Valsartan should not be taken if you are allergic to it or any ingredients used to make this drug.

Breastfeeding and pregnancy: Valsartan can harm an unborn child and pass to the breast milk. As a result, using these drugs while pregnant is not advised.

Liver or kidney disease: Valsartan might affect liver or kidney function, so you should tell your doctor if you have a history of liver or kidney illness before taking this medicine.

Low blood pressure: Because Valsartan can drop blood pressure, you should let your healthcare provider know in case you have low blood pressure or taking any other blood pressure-lowering drugs.

Heart disease: Before taking Valsartan, you should let your doctor know if you have any history of heart illness, such as a heart attack, stroke, or heart failure.

Diabetes: If you have diabetes, you should regularly check your blood sugar levels while taking Valsartan because it can have an impact on your body.

Surgery: If you are going for surgery, you should let your doctor know that you are taking Valsartan since it may interact with some anesthetic drugs.

When using Valsartan, it’s crucial to adhere to your doctor’s instructions and safety precautions, as well as to let them know about any current or past illnesses or medications you’re taking.

Chemical composition of Valsartan

Valsartan structure

It is an angiotensin blocker medication used to treat high blood pressure and heart failure. The chemical name is N-(1-oxopentyl)-N-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]-L-valine.

The chemical formula of Vlasartan is C24H29N5O3, and the molecular weight is 435.5g/mol.

The chemical structure of Valsartan consists of a tetrazole ring, valine amino acid residue, and biphenyl moiety. The molecular formula indicates that it contains 24 carbon atoms, 29 hydrogen atoms, three oxygen atoms, and five nitrogen atoms. 

The IUPAC name of Valsartan is 3-methyl-2-[pentanoyl-[[2′-(1H-tetrazol-5-yl)[1,1′-biphenyl]-4-yl]methyl]amino]butanoic acid.

Overall, it is a complex molecule with a specific arrangement of atoms and functional groups which contribute to the therapeutic property of the drugs. 


We tried to sum up all the information related to Valsartan, if you have any queries regarding any of the compositions, you can always reach out to us. Bulat Pharmaceuticals is here to solve all your queries. Contact us today.


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